Posts Tagged ‘XEOMIN’

New Botulinum Toxin Could Drive Prices Down

Wednesday, July 13th, 2011

Last summer, the FDA granted approval for the botulinum toxin drug XEOMIN to treat abnormal neck pain (cervical dystonia) and spasms of the eye. XEOMIN is botulinum toxin type a, the same active ingredient used in Botox® Cosmetic.

When it receives approval for cosmetic use, it could create enough competition in the market to drive down prices on all botulinum toxin injections.

Current treatment prices for Botox® range from $9 to $15 per unit, with most patients requiring about 20 units per treatment area.  These prices could drop when XEOMIN receives cosmetic approval from the FDA. Although XEOMIN isn’t believed to be superior, doctors say it could create more options, more competition and thus, lower prices.

“Current off-label use hasn’t shown any particular clinical advantage for Xeomin over Botox (onabotulinumtoxinA, Allergan) or Dysport, but the new toxin will broaden clinicians’ aesthetic options and may spur price competition in the U.S. “

Quote Via Dermatology Times

With another contender in this already competitive market, consumers may see more rebates and more price breaks from the pharmaceutical companies.

XEOMIN is the 3rd botulinum toxin to receive FDA approval in the U.S. The fourth could be PurTox, a drug by Mentor (popular breast implant manufacturer) that is still being studied.

You can read all the facts on the new website XEOMIN.com, including “How XEOMIN works.”

“XEOMIN is injected into muscles to decrease their activity. XEOMIN blocks the release of a chemical messenger—acetylcholine—that conveys the signal from nerve terminals and causes muscle fibers to contract. Not all terminals are affected by botulinum toxin, so the muscles can still contract, just less forcefully. This allows the muscles to contract more normally.”

XEOMIN Botulinum Toxin Approved for Treatment of Eyelid Spasms

Wednesday, August 4th, 2010

injectablesXEOMIN is a botulinum toxin type A product that has just been approved by the FDA for the treatment of adults with cervical dystonia or blepharospasm. Other products of this type approved in the U.S. are Botox and Dysport.

XEOMINa product of Merz Pharmaceuticalsreceived FDA approval based on the results of two U.S. clinical trials. In addition, a study cited in the Journal of Neurological Sciences said XEOMIN showed “non-inferiority” to Botox when used in the same doses to treat cervical dystonia, concluding it is a safe and effective treatment for the disorder, which is a neurological movement disorder in which sustained muscle contractions cause twisting of the neck. XEOMIN is also approved to treat excessive eyelid spasms (blepharospasm).

While XEOMIN has not been approved for cosmetic purposes, it could be in the future, and until then doctors may start to offer it as an off-label option to patients.

XEOMIN differs from Botox and Dysport in that it doesn’t require refrigeration prior to reconstitution. Merz believes this quality may “simplify product distribution and storage and help ensure product integrity at the time of injection.”

In early 2010, Merz announced it would be acquiring BioForm Medical, maker of the Radiesse dermal filler. Following completion of the acquisition of, Merz will be rebranded “Merz Aesthetics.”

Despite more competition, Botox does not show signs of slowing. An earnings release from Allergan this week reported that Botox sales rose 7 percent in the quarter to $360.5 million. Additionally, the Allergan report noted that the FDA has extended a review of Botox as a migraine therapy by three months. If approved for use as a migraine treatment, Botox sales could expand even further.